Survival Analysis: Kaplan-Meier Plots
Kaplan-Meier graphs are visual representations of survival data, commonly used in medical research and other fields dealing with time-to-event data. They illustrate the probability of an event (like death or disease recurrence) occurring over time, providing a clear picture of survival rates within a group. These graphs display survival curves, where the y-axis shows the proportion of subjects who survived past a certain point in time, and the x-axis represents time. Steps or drops in the curve indicate the occurrence of events. Kaplan-Meier curves are essential tools for comparing survival experiences between different groups, such as patients receiving various treatments or possessing different characteristics.
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var data = [
[ "Id", "Age", "Clin2", "Clin3", "Survival", "Survival-Censor", "Survival2", "Survival2-Censor", "Clin4", "HPV", "Sex", "Clasification", "Clin1", "Region", "Drug", "Stage", "Smoking"],
[ "Sub-1", 66, 1, 234, 12.4, 0, 1.6, 0, ">=1", "Pos", "M", "PD", "Y", "North America", "Drug1", "IV", "Unknown"],
[ "Sub-2", 59, 1, 123, 21.4, 0, 21.4, 0, ">=1", "Nor Reported", "F", "NE", "Y", "North America", "Drug2", "III", "No"],
[ "Sub-3", 66, 1, 173, 12.9, 0, 1.8, 0, "<1", "Pos", "M", "PD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-4", 66, 1, 150, 18.5, 1, 3.3, 0, "<1", "Pos", "M", "SD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-5", 63, 1, 95, 2.9, 0, 2.9, 0, "", "Nor Reported", "M", "SD", "Y", "North America", "Drug3", "IV", "Yes"],
[ "Sub-6", 50, 1, null, 3.7, 0, 1.7, 0, "<1", "Pos", "M", "PD", "N", "North America", "Drug4", "IV", "Yes"],
[ "Sub-7", 53, 1, 122, 10.2, 0, 1.8, 1, ">=1", "Nor Reported", "M", "SD", "Y", "North America", "Drug2", "IV", "Yes"],
[ "Sub-8", 49, 1, 119, 15, 1, 0, 1, "", "Nor Reported", "M", "NE", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-9", 29, 1, 114, 8, 0, 3.1, 0, "", "Nor Reported", "F", "SD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-10", 49, 1, 478, 22.7, 1, 1.9, 0, "<1", "Nor Reported", "M", "PD", "Y", "North America", "Drug1", "IV", "Yes"],
[ "Sub-11", 67, 0, 188, 24.5, 1, 23.3, 1, "<1", "Pos", "M", "CR", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-12", 57, 0, 180, 3.8, 0, 2, 0, ">=1", "Pos", "M", "PD", "Y", "North America", "Drug1", "IV", "No"],
[ "Sub-13", 69, 1, 178, 7.2, 0, 4.7, 0, "<1", "Pos", "M", "SD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-14", 59, 1, 166, 24.5, 1, 7.7, 0, "", "Pos", "M", "SD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-15", 55, 0, 300, 2.1, 0, 2.1, 0, ">=1", "Pos", "M", "NE", "Y", "North America", "Drug2", "IV", "Yes"],
[ "Sub-16", 55, 1, 153, 2.3, 0, 2.3, 0, "", "Neg", "M", "SD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-17", 55, 0, 174, 19.5, 0, 1.9, 0, "<1", "Neg", "M", "PD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-18", 59, 1, 112, 5.2, 0, 1.8, 0, "<1", "Nor Reported", "M", "PD", "Y", "North America", "Drug2", "IV", "Yes"],
[ "Sub-19", 67, 1, 317, 7.1, 0, 3.2, 0, "<1", "Neg", "M", "SD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-20", 66, 0, 151, 9.8, 0, 2, 0, "<1", "Pos", "M", "PD", "N", "North America", "Drug4", "IV", "No"],
[ "Sub-21", 59, 1, 211, 20.2, 1, 6.4, 1, ">=1", "Neg", "M", "PR", "Y", "North America", "Drug2", "IV", "Yes"],
[ "Sub-22", 54, 0, 175, 3.9, 0, 2, 0, ">=1", "Neg", "M", "PD", "Y", "North America", "Drug1", "IV", "Yes"],
[ "Sub-23", 58, 1, 323, 9.9, 0, 1.8, 0, "", "Pos", "M", "PD", "Y", "North America", "Drug2", "IV", "Yes"],
[ "Sub-24", 60, 0, 137, 5.2, 0, 1.6, 0, "<1", "Neg", "M", "PD", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-25", 79, 1, 94, 2.6, 0, 2.6, 0, "", "Nor Reported", "M", "NE", "N", "North America", "Drug2", "IV", "Yes"],
[ "Sub-26", 58, 0, 182, 16.7, 1, 15.6, 1, "", "Nor Reported", "M", "CR", "N", "North America", "Drug2", "III", "No"],
[ "Sub-27", 53, 1, 211, 13, 0, 1.8, 0, "<1", "Neg", "M", "PD", "Y", "North America", "Drug2", "IV", "Yes"],
[ "Sub-28", 57, 0, 195, 8.3, 0, 1.8, 0, "<1", "Pos", "M", "PD", "N", "North America", "Drug4", "IV", "Yes"],
// ... (data truncated after 29 records for clarity)
]
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"graphType" : "Scatter2D",
"invertCensored" : true,
"showKMConfidenceIntervals" : false,
"xAxisTitle" : "Weeks",
"xAxis" : ["Survival","Survival-Censor"],
"yAxisTitle" : "Probability of Survival"
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}
}
// Create the configuration for the graph
var config = {
"colorBy" : "Sex",
"graphType" : "Scatter2D",
"invertCensored" : true,
"showKMConfidenceIntervals" : false,
"xAxisTitle" : "Weeks",
"xAxis" : ["Survival","Survival-Censor"],
"yAxisTitle" : "Probability of Survival"
}
// Event used to create graph (optional)
var events = false
// Call the CanvasXpress function to create the graph
var cX = new CanvasXpress("canvasId", data, config, events);
// Functions after rendering graph
cX.switchSmpToAnnotation('Age');
cX.switchSmpToAnnotation('Clin2');
cX.switchSmpToAnnotation('Clin3');
cX.addKMPlot();
cX.createDOE();
</script>
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